Paula has been honored with the prestigious SSR Trainee Mentoring Award from the Society for the Study of Reproduction (SSR)...

Saloni Dhopte, a graduate student in Genetics, Genomics, and Development (GGD), has joined both the Cohen and Danko Labs. Saloni will be studying the mechanisms..

Summer 2024 proved to be an exceptional conference season for the Cohen Lab, with members attending four prestigious conferences spanning the USA and Europe...

Recent studies emphasize the importance of ubiquitination and SUMOylation pathways in CO formation. E3 ligases RNF212 and HEI10 are indispensable for CO selection and maturation. Recently, genome-wide association studies have identified a novel E3 ligase, RNF212B...

Virtually all crossovers are made by the mismatch repair proteins, MSH4/MSH5 (MutSγ) and MLH1/MLH3 (MutLγ). However, the number of crossover intermediates (~140 MSH4 foci) far exceeds the final number of crossovers (24-26 in male mice). The mechanisms regulating the selection of which intermediates maturate into crossovers remains poorly understood...

Meiotic sex chromosome inactivation (MSCI) is a critical feature of meiotic prophase I progression in males. While the ATR kinase and its activator TOPBP1 are key drivers of MSCI within the specialized sex body (SB) domain of the nucleus, how they promote silencing remains unclear given their multifaceted meiotic functions....